BDBM50316597 CHEMBL1098671::N-((S)-1-((2S,3S)-3-hydroxy-5-oxo-5-((S)-1-oxo-3-phenyl-1-(prop-2-ynylamino)propan-2-ylamino)-1-phenylpentan-2-ylamino)-3-methyl-1-oxobutan-2-yl)picolinamide

SMILES CC(C)[C@H](NC(=O)c1ccccn1)C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)CC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#C

InChI Key InChIKey=RAZZBARIWRCYLK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50316597   

TargetPlasmepsin II(Plasmodium falciparum)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50316597(N-((S)-1-((2S,3S)-3-hydroxy-5-oxo-5-((S)-1-oxo-3-p...)
Affinity DataIC50: 22nMAssay Description:Competitive inhibition of Plasmodium falciparum plasmepsin-2 expressed in Escherichia coli BL21 (DE3) after 30 min by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCathepsin D(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50316597(N-((S)-1-((2S,3S)-3-hydroxy-5-oxo-5-((S)-1-oxo-3-p...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human cathepsin D after 30 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50316597(N-((S)-1-((2S,3S)-3-hydroxy-5-oxo-5-((S)-1-oxo-3-p...)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant Plasmodium falciparum Plasmepsin 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed