BDBM50316543 CHEMBL1094197::N,N'-(Propane-1,3-diyl)bis(6,7-dihydroxy-2-imino-2H-chromene-3-carboxamide)

SMILES Oc1cc2cc(C(=O)NCCCNC(=O)c3cc4cc(O)c(O)cc4oc3=N)c(=N)oc2cc1O

InChI Key InChIKey=FKOFIPBOYPUDNV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50316543   

TargetDynamin-2(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316543(N,N'-(Propane-1,3-diyl)bis(6,7-dihydroxy-2-imino-2...)
Affinity DataIC50: 290nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells by malachite green GTPase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetDynamin-2(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316543(N,N'-(Propane-1,3-diyl)bis(6,7-dihydroxy-2-imino-2...)
Affinity DataIC50: 7.46E+4nMAssay Description:Inhibition of dynamin 2-mediated receptor-induced endocytosis in human U2OS cells assessed as uptake of Tf-TxR dye after 30 mins by automated acquisi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetDynamin-1(Rat)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316543(N,N'-(Propane-1,3-diyl)bis(6,7-dihydroxy-2-imino-2...)
Affinity DataIC50: 4.04E+4nMAssay Description:Inhibition of dynamin 1-mediated synaptic vesicle endocytosis in Sprague-Dawley rat synaptosomes assessed as uptake of FM 4-64 dye after 30 mins by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed