BDBM50316517 CHEMBL1169572::N-[6-(4-Chlorophenyl)-7-(2,4-dichlorophenyl)-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]pyridine-4-yl]-3,3,3-trifluoro-2-hydroxypropanamide

SMILES Cc1cc(Cl)ccc1-c1nc2OC(C)(C)CC(NC(=O)C(O)C(F)(F)F)c2cc1-c1ccc(Cl)cc1

InChI Key InChIKey=CHLLVQZFMABVHW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50316517   

TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50316517(N-[6-(4-Chlorophenyl)-7-(2,4-dichlorophenyl)-2,2-d...)
Affinity DataIC50: 1.80nMAssay Description:Displacement of [3H]CP-55940 from human recombinant cannabinoid CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50316517(N-[6-(4-Chlorophenyl)-7-(2,4-dichlorophenyl)-2,2-d...)
Affinity DataIC50: 1.80nMAssay Description:Displacement of [3H]CP-55940 from human recombinant cannabinoid CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50316517(N-[6-(4-Chlorophenyl)-7-(2,4-dichlorophenyl)-2,2-d...)
Affinity DataIC50: 3.40E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant cannabinoid CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50316517(N-[6-(4-Chlorophenyl)-7-(2,4-dichlorophenyl)-2,2-d...)
Affinity DataIC50: 3.40E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant cannabinoid CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50316517(N-[6-(4-Chlorophenyl)-7-(2,4-dichlorophenyl)-2,2-d...)
Affinity DataIC50: 260nMAssay Description:Displacement of [35S]MK499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50316517(N-[6-(4-Chlorophenyl)-7-(2,4-dichlorophenyl)-2,2-d...)
Affinity DataIC50: 260nMAssay Description:Displacement of [35S]MK499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed