BDBM50316321 CHEMBL1096276::rac-1-{3-[4-(2-Methoxyphenyl)piperazin-1-yl]propyl}-2',3'-dihydrospiro[imidazolidine-4,1'-indene]-2,5-dione

SMILES COc1ccccc1N1CCN(CCCN2C(=O)NC3(CCc4ccccc34)C2=O)CC1

InChI Key InChIKey=SBKHEDZZMPNVER-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50316321   

Target5-hydroxytryptamine receptor 1A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50316321(rac-1-{3-[4-(2-Methoxyphenyl)piperazin-1-yl]propyl...)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]8OH-DPAT from 5HT1A in rat brain cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50316321(rac-1-{3-[4-(2-Methoxyphenyl)piperazin-1-yl]propyl...)
Affinity DataKi:  653nMAssay Description:Displacement of [3H]ketanserin from 5HT2A in rat brain cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50316321(rac-1-{3-[4-(2-Methoxyphenyl)piperazin-1-yl]propyl...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [3H]Citalopram from SERT in rat cerebral cortex after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed