BDBM50316188 4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-6-(pyrrolidin-1-ylmethyl)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol::CHEMBL1096290

SMILES CCn1c(nc2c(nc(CN3CCCC3)cc12)C#CC(C)(C)O)-c1nonc1N

InChI Key InChIKey=JHBURLBWOXZZGX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50316188   

TargetRAC-gamma serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50316188(4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-6-(pyr...)
Affinity DataIC50: 22nMAssay Description:Inhibition of AKT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50316188(4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-6-(pyr...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of GSK3-beta phosphorylation in human BT474 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50316188(4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-6-(pyr...)
Affinity DataIC50: 6nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50316188(4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-6-(pyr...)
Affinity DataIC50: 200nMAssay Description:Inhibition of AKT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed