BDBM50316186 4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-(aminomethyl)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol::CHEMBL1098241

SMILES CCn1c(nc2c(nc(CN)cc12)C#CC(C)(C)O)-c1nonc1N

InChI Key InChIKey=SAJJWJQNKYDEPD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50316186   

TargetRAC-gamma serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50316186(4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-(aminomethyl...)
Affinity DataIC50: 70nMAssay Description:Inhibition of AKT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50316186(4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-(aminomethyl...)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of GSK3-beta phosphorylation in human BT474 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50316186(4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-(aminomethyl...)
Affinity DataIC50: 63nMAssay Description:Inhibition of AKT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50316186(4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-(aminomethyl...)
Affinity DataIC50: 6nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed