BDBM50316049 1-amino-3-phenylpropylphosphonic acid::CHEMBL1090914

SMILES NC(CCc1ccccc1)P(O)(O)=O

InChI Key InChIKey=NAPHUBPIUWHFCT-UHFFFAOYSA-N

Data  6 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50316049   

TargetAminopeptidase N(Pig)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50316049(1-amino-3-phenylpropylphosphonic acid | CHEMBL1090...)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of pig kidney aminopeptidase N using Leu-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50316049(1-amino-3-phenylpropylphosphonic acid | CHEMBL1090...)
Affinity DataKi:  790nMAssay Description:Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50316049(1-amino-3-phenylpropylphosphonic acid | CHEMBL1090...)
Affinity DataKi:  3.96E+3nMAssay Description:Inhibition of pig recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetCytosol aminopeptidase [33-68,L62W](Pig)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50316049(1-amino-3-phenylpropylphosphonic acid | CHEMBL1090...)
Affinity DataKi:  4.55E+3nMAssay Description:Inhibition of pig recombinant leucine aminopeptidase after 30 to 60 mins by morrison's equationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50316049(1-amino-3-phenylpropylphosphonic acid | CHEMBL1090...)
Affinity DataKi:  1.59E+4nMAssay Description:Inhibition of pig kidney microsomal aminopeptidase NMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50316049(1-amino-3-phenylpropylphosphonic acid | CHEMBL1090...)
Affinity DataKi:  2.69E+4nMAssay Description:Inhibition of recombinant human ERAP1 using L-AMC as substrate measured for 15 to 30 mins by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2017
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50316049(1-amino-3-phenylpropylphosphonic acid | CHEMBL1090...)
Affinity DataKi: >2.50E+5nMAssay Description:Inhibition of human ERAP2 preincubated for 30 to 60 mins followed by addition of Arg-AMC as substrate measured for 15 mins by spectrofluorimetric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2017
Entry Details Article
PubMed