BDBM50315965 CHEMBL1092097::N-(3,4-difluorophenylsulfonyl)-3-(4-(morpholinomethyl)-2-(2-(naphthalen-2-yl)ethoxy)phenyl)propanamide

SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)CCc1ccc(CN2CCOCC2)cc1OCCc1ccc2ccccc2c1

InChI Key InChIKey=KQZKVHKRCBRXPF-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50315965   

TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315965(N-(3,4-difluorophenylsulfonyl)-3-(4-(morpholinomet...)
Affinity DataIC50: 47nMAssay Description:Antagonist activity at mouse EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315965(N-(3,4-difluorophenylsulfonyl)-3-(4-(morpholinomet...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315965(N-(3,4-difluorophenylsulfonyl)-3-(4-(morpholinomet...)
Affinity DataKi:  5.00E+3nMAssay Description:Displacement of [3H]PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315965(N-(3,4-difluorophenylsulfonyl)-3-(4-(morpholinomet...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315965(N-(3,4-difluorophenylsulfonyl)-3-(4-(morpholinomet...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed