BDBM50315964 CHEMBL1090938::N-(3,4-difluorophenylsulfonyl)-3-(4-((dimethylamino)methyl)-2-(2-(naphthalen-2-yl)ethoxy)phenyl)propanamide

SMILES CN(C)Cc1ccc(CCC(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c(OCCc2ccc3ccccc3c2)c1

InChI Key InChIKey=XFEQJTJHYVKTOT-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50315964   

TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315964(N-(3,4-difluorophenylsulfonyl)-3-(4-((dimethylamin...)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at mouse EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315964(N-(3,4-difluorophenylsulfonyl)-3-(4-((dimethylamin...)
Affinity DataKi:  8.20nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315964(N-(3,4-difluorophenylsulfonyl)-3-(4-((dimethylamin...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315964(N-(3,4-difluorophenylsulfonyl)-3-(4-((dimethylamin...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315964(N-(3,4-difluorophenylsulfonyl)-3-(4-((dimethylamin...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed