BDBM50315834 1-phenyl-N-(3-styryl-1H-indazol-5-yl)methanesulfonamide::CHEMBL1093514

SMILES O=S(=O)(Cc1ccccc1)Nc1ccc2[nH]nc(\C=C\c3ccccc3)c2c1

InChI Key InChIKey=GCKBOFRETXSMFP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315834   

TargetAurora kinase B(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315834(1-phenyl-N-(3-styryl-1H-indazol-5-yl)methanesulfon...)
Affinity DataIC50: 31nMAssay Description:Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50315834(1-phenyl-N-(3-styryl-1H-indazol-5-yl)methanesulfon...)
Affinity DataIC50: 35nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminescenceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed