BDBM50315820 2-Amino-4-(4'-benzylthio-2'-fluorobiphenyl-4-yl)-2-(phosphoryloxymethyl)butanol::CHEMBL1090819

SMILES NC(CO)(CCc1ccc(cc1)-c1ccc(SCc2ccccc2)cc1F)COP(O)(O)=O

InChI Key InChIKey=DVJSZJXGRALSDM-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315820   

TargetSphingosine 1-phosphate receptor 1(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50315820(2-Amino-4-(4'-benzylthio-2'-fluorobiphenyl-4-yl)-2...)
Affinity DataEC50:  0.840nMAssay Description:Agonist activity at human S1P1 receptor expressed in human Chem1 cells assessed as intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50315820(2-Amino-4-(4'-benzylthio-2'-fluorobiphenyl-4-yl)-2...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed