BDBM50315777 3-(4-Acetyl-phenyl)-2-(5-morpholin-4-yl-4-pyridin-4-yl-thiophen-2-yl)-3H-quinazolin-4-one::CHEMBL1093503

SMILES CC(=O)c1ccc(cc1)-n1c(nc2ccccc2c1=O)-c1cc(c(s1)N1CCOCC1)-c1ccncc1

InChI Key InChIKey=RAJQBCXLPLDSMH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315777   

TargetTranscription factor Jun(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50315777(3-(4-Acetyl-phenyl)-2-(5-morpholin-4-yl-4-pyridin-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of AP-1-mediated transcriptional activation in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetTranscription factor Jun(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50315777(3-(4-Acetyl-phenyl)-2-(5-morpholin-4-yl-4-pyridin-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of AP-1 expressed in HEK293 cells assessed as PMA-stimulated transcriptional activation treated 24 hrs before PMA challenge measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed