BDBM50315652 CHEMBL1090143::N-(3-(6-(pyridin-4-yl)thieno[2,3-d]pyrimidin-4-yl)phenyl)-3-(trifluoromethyl)benzamide

SMILES FC(F)(F)c1cccc(c1)C(=O)Nc1cccc(c1)-c1ncnc2sc(cc12)-c1ccncc1

InChI Key InChIKey=CXIYVOOQCNGGIB-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50315652   

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(N-(3-(6-(pyridin-4-yl)thieno[2,3-d]pyrimidin-4-yl)...)
Affinity DataIC50: 80nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315652(N-(3-(6-(pyridin-4-yl)thieno[2,3-d]pyrimidin-4-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IKK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(N-(3-(6-(pyridin-4-yl)thieno[2,3-d]pyrimidin-4-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(N-(3-(6-(pyridin-4-yl)thieno[2,3-d]pyrimidin-4-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(N-(3-(6-(pyridin-4-yl)thieno[2,3-d]pyrimidin-4-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ITKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(N-(3-(6-(pyridin-4-yl)thieno[2,3-d]pyrimidin-4-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(N-(3-(6-(pyridin-4-yl)thieno[2,3-d]pyrimidin-4-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BTKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(N-(3-(6-(pyridin-4-yl)thieno[2,3-d]pyrimidin-4-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SRCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(N-(3-(6-(pyridin-4-yl)thieno[2,3-d]pyrimidin-4-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LYNMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315652(N-(3-(6-(pyridin-4-yl)thieno[2,3-d]pyrimidin-4-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(N-(3-(6-(pyridin-4-yl)thieno[2,3-d]pyrimidin-4-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315652(N-(3-(6-(pyridin-4-yl)thieno[2,3-d]pyrimidin-4-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315652(N-(3-(6-(pyridin-4-yl)thieno[2,3-d]pyrimidin-4-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed