BDBM50315642 CHEMBL1091267::N-[2-(4-Bromophenyl)-8-phenylethyl-pyrazolo[4,3-e][1,2,4]-triazolo[1,5-c]pyrimidin-5-yl]benzamide

SMILES Brc1ccc(cc1)-c1nc2c3cn(CCc4ccccc4)nc3nc(NC(=O)c3ccccc3)n2n1

InChI Key InChIKey=PCEGTWAEMUHEIY-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50315642   

TargetAdenosine receptor A3(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50315642(N-[2-(4-Bromophenyl)-8-phenylethyl-pyrazolo[4,3-e]...)
Affinity DataKi:  153nMAssay Description:Displacement of [3H]NECA from human cloned adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50315642(N-[2-(4-Bromophenyl)-8-phenylethyl-pyrazolo[4,3-e]...)
Affinity DataKi:  270nMAssay Description:Displacement of [3H]CCPA from human cloned adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50315642(N-[2-(4-Bromophenyl)-8-phenylethyl-pyrazolo[4,3-e]...)
Affinity DataKi: >1.00E+4nMAssay Description:Antagonist activity at human cloned adenosine A2b receptor expressed in CHO cells assessed as inhibition of NECA-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50315642(N-[2-(4-Bromophenyl)-8-phenylethyl-pyrazolo[4,3-e]...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]NECA from human cloned adenosine A2a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed