BDBM50315641 CHEMBL1093202::N-[2-(Phenyl)-8-phenylethyl-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-yl]benzamide

SMILES O=C(Nc1nc2nn(CCc3ccccc3)cc2c2nc(nn12)-c1ccccc1)c1ccccc1

InChI Key InChIKey=VSWCOBIDKGRDKM-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50315641   

TargetAdenosine receptor A3(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50315641(N-[2-(Phenyl)-8-phenylethyl-pyrazolo[4,3-e][1,2,4]...)
Affinity DataKi:  23.9nMAssay Description:Displacement of [3H]NECA from human cloned adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50315641(N-[2-(Phenyl)-8-phenylethyl-pyrazolo[4,3-e][1,2,4]...)
Affinity DataKi:  313nMAssay Description:Displacement of [3H]CCPA from human cloned adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50315641(N-[2-(Phenyl)-8-phenylethyl-pyrazolo[4,3-e][1,2,4]...)
Affinity DataKi:  963nMAssay Description:Displacement of [3H]NECA from human cloned adenosine A2a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50315641(N-[2-(Phenyl)-8-phenylethyl-pyrazolo[4,3-e][1,2,4]...)
Affinity DataKi: >1.00E+4nMAssay Description:Antagonist activity at human cloned adenosine A2b receptor expressed in CHO cells assessed as inhibition of NECA-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed