BDBM50315621 2-(4-Fluorophenyl)-8-methylpyrazolo[4,3-e]1,2,4-triazolo[1,5-c]-pyrimidin-5-amine::CHEMBL1090489

SMILES Cn1cc2c(n1)nc(N)n1nc(nc21)-c1ccc(F)cc1

InChI Key InChIKey=HNASIMBMXSXIHF-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50315621   

TargetAdenosine receptor A3(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50315621(2-(4-Fluorophenyl)-8-methylpyrazolo[4,3-e]1,2,4-tr...)
Affinity DataKi:  31.4nMAssay Description:Displacement of [3H]NECA from human cloned adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50315621(2-(4-Fluorophenyl)-8-methylpyrazolo[4,3-e]1,2,4-tr...)
Affinity DataKi:  355nMAssay Description:Displacement of [3H]NECA from human cloned adenosine A2a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50315621(2-(4-Fluorophenyl)-8-methylpyrazolo[4,3-e]1,2,4-tr...)
Affinity DataKi:  1.01E+3nMAssay Description:Displacement of [3H]CCPA from human cloned adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50315621(2-(4-Fluorophenyl)-8-methylpyrazolo[4,3-e]1,2,4-tr...)
Affinity DataKi: >1.00E+4nMAssay Description:Antagonist activity at human cloned adenosine A2b receptor expressed in CHO cells assessed as inhibition of NECA-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed