BDBM50315600 5-Dimethylamino-2-(2-furyl)-7-n-pentylcarbonylamino-[1,2,4]triazolo[1,5-a]-[1,3,5]triazine::CHEMBL1089798

SMILES CCCCCC(=O)Nc1nc(nc2nc(nn12)-c1ccco1)N(C)C

InChI Key InChIKey=MXGNPZRQEUOQFW-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50315600   

TargetAdenosine receptor A2b(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50315600(5-Dimethylamino-2-(2-furyl)-7-n-pentylcarbonylamin...)
Affinity DataEC50: >1.00E+5nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated adenylyl cyclase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50315600(5-Dimethylamino-2-(2-furyl)-7-n-pentylcarbonylamin...)
Affinity DataKi:  1.57E+3nMAssay Description:Displacement of [3H]R-PIA from adenosine A1 receptor in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50315600(5-Dimethylamino-2-(2-furyl)-7-n-pentylcarbonylamin...)
Affinity DataKi:  2.20E+3nMAssay Description:Displacement of [125I]-I-AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50315600(5-Dimethylamino-2-(2-furyl)-7-n-pentylcarbonylamin...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CGS21680 from adenosine A2A receptor in rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed