BDBM50315595 CHEMBL1089440::N-(2-(furan-2-yl)-5-phenoxy-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl)hexanamide

SMILES O=C(Nc1ccccc1)Nc1nc(Oc2ccccc2)nc2nc(nn12)-c1ccco1

InChI Key InChIKey=OAANTUPREZEYHE-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50315595   

TargetAdenosine receptor A2b(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50315595(N-(2-(furan-2-yl)-5-phenoxy-[1,2,4]triazolo[1,5-a]...)
Affinity DataEC50:  8.87E+3nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated adenylyl cyclase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50315595(N-(2-(furan-2-yl)-5-phenoxy-[1,2,4]triazolo[1,5-a]...)
Affinity DataKi:  38.9nMAssay Description:Displacement of [3H]CGS21680 from adenosine A2A receptor in rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50315595(N-(2-(furan-2-yl)-5-phenoxy-[1,2,4]triazolo[1,5-a]...)
Affinity DataKi:  633nMAssay Description:Displacement of [125I]-I-AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed