BDBM50315593 2-(2-Furyl)-7-[4-(methoxyphenyl)acetyl]amino-5-phenoxy[1,2,4]triazolo[1,5-a]-[1,3,5]triazine::CHEMBL1089438

SMILES COc1ccc(CC(=O)Nc2nc(Oc3ccccc3)nc3nc(nn23)-c2ccco2)cc1

InChI Key InChIKey=PSVHAWJNCNBNAP-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50315593   

TargetAdenosine receptor A2b(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50315593(2-(2-Furyl)-7-[4-(methoxyphenyl)acetyl]amino-5-phe...)
Affinity DataEC50: >1.00E+5nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated adenylyl cyclase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50315593(2-(2-Furyl)-7-[4-(methoxyphenyl)acetyl]amino-5-phe...)
Affinity DataKi:  892nMAssay Description:Displacement of [3H]CGS21680 from adenosine A2A receptor in rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50315593(2-(2-Furyl)-7-[4-(methoxyphenyl)acetyl]amino-5-phe...)
Affinity DataKi:  5.20E+3nMAssay Description:Displacement of [125I]-I-AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed