BDBM50315550 (S)-2-amino-3-(4-(3-(biphenyl-4-yl)propanoyl)phenylamino)-2-methyl-3-oxopropyl dihydrogen phosphate::CHEMBL1090796

SMILES C[C@](N)(COP(O)(O)=O)C(=O)Nc1ccc(cc1)C(=O)CCc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=KNLPKQCGTFMRRN-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50315550   

TargetSphingosine 1-phosphate receptor 1(Human)
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50315550((S)-2-amino-3-(4-(3-(biphenyl-4-yl)propanoyl)pheny...)
Affinity DataIC50: 4.14nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P1 receptor expressed in HEK293T cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50315550((S)-2-amino-3-(4-(3-(biphenyl-4-yl)propanoyl)pheny...)
Affinity DataIC50: 3.80E+3nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P3 receptor expressed in HEK293T cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50315550((S)-2-amino-3-(4-(3-(biphenyl-4-yl)propanoyl)pheny...)
Affinity DataIC50: 13.1nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P4 receptor expressed in HEK293T cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50315550((S)-2-amino-3-(4-(3-(biphenyl-4-yl)propanoyl)pheny...)
Affinity DataIC50: 1.36E+3nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P5 receptor expressed in HEK293T cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50315550((S)-2-amino-3-(4-(3-(biphenyl-4-yl)propanoyl)pheny...)
Affinity DataEC50:  18.3nMAssay Description:Antagonist activity at human S1P1 receptor expressed in HEK293T cells assessed as inhibition of sphingosine-1-phosphate-induced gamma-[35S]GTP bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50315550((S)-2-amino-3-(4-(3-(biphenyl-4-yl)propanoyl)pheny...)
Affinity DataEC50: >3.00E+3nMAssay Description:Antagonist activity at human S1P3 receptor expressed in HEK293T cells assessed as inhibition of sphingosine-1-phosphate-induced gamma-[35S]GTP bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed