BDBM50315464 4,6-dihydroxy-2-((1-(2-(4-(3-hydroxypropyl)piperazin-1-yl)ethyl)-5-methoxy-1H-indol-3-yl)methylene)benzofuran-3(2H)-one::CHEMBL1090131

SMILES COc1ccc2n(CCN3CCN(CCCO)CC3)cc(\C=C3/Oc4cc(O)cc(O)c4C3=O)c2c1

InChI Key InChIKey=LKJWRWGSGQGEJA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50315464   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315464(4,6-dihydroxy-2-((1-(2-(4-(3-hydroxypropyl)piperaz...)
Affinity DataIC50: 215nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315464(4,6-dihydroxy-2-((1-(2-(4-(3-hydroxypropyl)piperaz...)
Affinity DataIC50: 36nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315464(4,6-dihydroxy-2-((1-(2-(4-(3-hydroxypropyl)piperaz...)
Affinity DataIC50: 976nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed