BDBM50315460 4,6-dihydroxy-2-((1-(2-(4-(3-hydroxypropyl)piperazin-1-yl)ethyl)-5-methoxy-2-methyl-1H-indol-3-yl)methylene)benzofuran-3(2H)-one::CHEMBL1090505

SMILES COc1ccc2n(CCN3CCN(CCCO)CC3)c(C)c(\C=C3/Oc4cc(O)cc(O)c4C3=O)c2c1

InChI Key InChIKey=OSMLKVXABIPDHD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50315460   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315460(4,6-dihydroxy-2-((1-(2-(4-(3-hydroxypropyl)piperaz...)
Affinity DataIC50: 7nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315460(4,6-dihydroxy-2-((1-(2-(4-(3-hydroxypropyl)piperaz...)
Affinity DataIC50: 4nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315460(4,6-dihydroxy-2-((1-(2-(4-(3-hydroxypropyl)piperaz...)
Affinity DataIC50: 322nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed