BDBM50315457 4,6-dihydroxy-2-((1-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)-5-methoxy-1H-indol-3-yl)methylene)benzofuran-3(2H)-one::CHEMBL1091854

SMILES COc1ccc2n(CCCN3CCN(CCO)CC3)cc(\C=C3/Oc4cc(O)cc(O)c4C3=O)c2c1

InChI Key InChIKey=XZLMDULFAHJEDT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50315457   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315457(4,6-dihydroxy-2-((1-(3-(4-(2-hydroxyethyl)piperazi...)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315457(4,6-dihydroxy-2-((1-(3-(4-(2-hydroxyethyl)piperazi...)
Affinity DataIC50: 37nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315457(4,6-dihydroxy-2-((1-(3-(4-(2-hydroxyethyl)piperazi...)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed