BDBM50315454 4,6-dihydroxy-2-((5-methoxy-2-methyl-1-(3-(4-methylpiperazin-1-yl)propyl)-1H-indol-3-yl)methylene)benzofuran-3(2H)-one::CHEMBL1093448

SMILES COc1ccc2n(CCCN3CCN(C)CC3)c(C)c(\C=C3/Oc4cc(O)cc(O)c4C3=O)c2c1

InChI Key InChIKey=MOULOOQEACIASM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50315454   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315454(4,6-dihydroxy-2-((5-methoxy-2-methyl-1-(3-(4-methy...)
Affinity DataIC50: 153nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315454(4,6-dihydroxy-2-((5-methoxy-2-methyl-1-(3-(4-methy...)
Affinity DataIC50: 15nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315454(4,6-dihydroxy-2-((5-methoxy-2-methyl-1-(3-(4-methy...)
Affinity DataIC50: 402nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed