BDBM50315422 (1S)-1,5-Anhydro-1-[3-(4-ethoxybenzyl)phenyl]-1-thio-D-glucitol::CHEMBL1092273

SMILES CCOc1ccc(Cc2cccc(c2)[C@@H]2S[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1

InChI Key InChIKey=GWUVCALZIGPECU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50315422   

TargetSodium/glucose cotransporter 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315422((1S)-1,5-Anhydro-1-[3-(4-ethoxybenzyl)phenyl]-1-th...)
Affinity DataIC50: 2.61E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315422((1S)-1,5-Anhydro-1-[3-(4-ethoxybenzyl)phenyl]-1-th...)
Affinity DataIC50: 74nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315422((1S)-1,5-Anhydro-1-[3-(4-ethoxybenzyl)phenyl]-1-th...)
Affinity DataIC50: 74nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 1 hr by mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315422((1S)-1,5-Anhydro-1-[3-(4-ethoxybenzyl)phenyl]-1-th...)
Affinity DataIC50: 2.61E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-methyl-alpha-D-glucopyranoside uptake after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed