BDBM50315411 4,7-Dichloro-1-benzothien-2-yl sulfonylaminomethyl boronic acid::CHEMBL1089781

SMILES OB(O)CNS(=O)(=O)c1cc2c(Cl)ccc(Cl)c2s1

InChI Key InChIKey=ZRZPQNCNBISJFG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50315411   

TargetBeta-lactamase SHV-5(Pseudomonas aeruginosa (g-Proteobacteria))
Merck

Curated by ChEMBL
LigandPNGBDBM50315411(4,7-Dichloro-1-benzothien-2-yl sulfonylaminomethyl...)
Affinity DataIC50: 570nMAssay Description:Inhibition of Klebsiella pneumoniae beta-lactamase SHV5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Merck

Curated by ChEMBL
LigandPNGBDBM50315411(4,7-Dichloro-1-benzothien-2-yl sulfonylaminomethyl...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa beta-lactamase AmpCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetBeta-lactamase(Enterobacter cloacae)
Merck

Curated by ChEMBL
LigandPNGBDBM50315411(4,7-Dichloro-1-benzothien-2-yl sulfonylaminomethyl...)
Affinity DataIC50: 620nMAssay Description:Inhibition of Enterobacter colacae P99 Beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetOxa40(Acinetobacter baumannii)
Merck

Curated by ChEMBL
LigandPNGBDBM50315411(4,7-Dichloro-1-benzothien-2-yl sulfonylaminomethyl...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of Acinetobacter baumannii beta-lactamase OXA40More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed