BDBM50315211 1-(4-(4,6-di((1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl)-1,3,5-triazin-2-yl)phenyl)-3-(4-(4-methylpiperazin-1-yl)phenyl)urea::CHEMBL1088972

SMILES CN1CCN(CC1)c1ccc(NC(=O)Nc2ccc(cc2)-c2nc(nc(n2)N2C[C@@H]3C[C@H]2CO3)N2C[C@@H]3C[C@H]2CO3)cc1

InChI Key InChIKey=VHMSKBYACVOPGE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50315211   

TargetSerine/threonine-protein kinase mTOR(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315211(1-(4-(4,6-di((1S,4S)-2-oxa-5-azabicyclo[2.2.1]hept...)
Affinity DataIC50: 35nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed