BDBM50315192 (R)-N,N-dimethyl-2-(3-(1-(4-methylthiazol-2-yl)ethyl)-1H-inden-2-yl)ethanamine::CHEMBL1092599

SMILES C[C@H](C1=C(CCN(C)C)Cc2ccccc12)c1nc(C)cs1

InChI Key InChIKey=SQDIKQKCDLMHCF-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50315192   

TargetCytochrome P450 2D6(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50315192((R)-N,N-dimethyl-2-(3-(1-(4-methylthiazol-2-yl)eth...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50315192((R)-N,N-dimethyl-2-(3-(1-(4-methylthiazol-2-yl)eth...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50315192((R)-N,N-dimethyl-2-(3-(1-(4-methylthiazol-2-yl)eth...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity at histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50315192((R)-N,N-dimethyl-2-(3-(1-(4-methylthiazol-2-yl)eth...)
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50315192((R)-N,N-dimethyl-2-(3-(1-(4-methylthiazol-2-yl)eth...)
Affinity DataKi:  3.60E+3nMAssay Description:Binding affinity at M1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed