BDBM50315132 4-(3-(3-chlorophenyl)-5-(1-methylpiperidin-4-yl)-1H-pyrazol-4-yl)pyridine::CHEMBL1092903

SMILES CN1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1cccc(Cl)c1

InChI Key InChIKey=RPEOVNFMEZECTP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315132   

TargetMitogen-activated protein kinase 11(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50315132(4-(3-(3-chlorophenyl)-5-(1-methylpiperidin-4-yl)-1...)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of p38beta assessed as gamma-[33P]ATP incorporation by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50315132(4-(3-(3-chlorophenyl)-5-(1-methylpiperidin-4-yl)-1...)
Affinity DataIC50: 39.2nMAssay Description:Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed