BDBM50315002 6-((2-(2-chlorophenyl)-5-(4-phenoxyphenyl)-1H-pyrrol-1-yl)methyl)pyridin-2-amine::CHEMBL1091343

SMILES Nc1cccc(Cn2c(ccc2-c2ccccc2Cl)-c2ccc(Oc3ccccc3)cc2)n1

InChI Key InChIKey=KFHXWAOFTXCHCN-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315002   

TargetBeta-secretase 1(Human)
Wyeth

Curated by ChEMBL
LigandPNGBDBM50315002(6-((2-(2-chlorophenyl)-5-(4-phenoxyphenyl)-1H-pyrr...)
Affinity DataIC50: 850nMAssay Description:Inhibition of human recombinant BACE1 expressed CHO cells by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Wyeth

Curated by ChEMBL
LigandPNGBDBM50315002(6-((2-(2-chlorophenyl)-5-(4-phenoxyphenyl)-1H-pyrr...)
Affinity DataEC50:  9.20E+3nMAssay Description:Inhibition of human recombinant APP in CHO cells assessed as decrease in beta amyloid protein level by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed