BDBM50314894 5-(5-methoxy-4-oxospiro[chroman-2,4'-piperidine]-1'-ylcarbonyl)-N-methyl-1H-indole-2-carboxamide::CHEMBL1089529

SMILES CNC(=O)c1cc2cc(ccc2[nH]1)C(=O)N1CCC2(CC1)CC(=O)c1c(OC)cccc1O2

InChI Key InChIKey=IVNARABLOZHGRS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314894   

TargetAcetyl-CoA carboxylase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314894(5-(5-methoxy-4-oxospiro[chroman-2,4'-piperidine]-1...)
Affinity DataIC50: 43nMAssay Description:Inhibition of rat liver ACC1 after 7 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314894(5-(5-methoxy-4-oxospiro[chroman-2,4'-piperidine]-1...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant ACC2 expressed in CHO cells after 1 hr by fluorescence readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed