BDBM50314874 CHEMBL4176611

SMILES [H][C@]12C[C@H](CC(=O)Nc3ccc(Cl)cc3)C=C[C@]1([C@H](\C=C(/Cl)c1ccc(cc1)C(O)=O)C=C(C)C2)C(=O)OC

InChI Key InChIKey=VVILYNHSRXZKRA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50314874   

TargetApoptosis regulator Bcl-2(Human)
Paris-Saclay University

Curated by ChEMBL
LigandPNGBDBM50314874(CHEMBL4176611)
Affinity DataKi:  700nMAssay Description:Inhibition of FITC-Ahx-Bim-OH binding to human Bcl2 isoform 2 after 2 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details Article
PubMed
LigandPNGBDBM50314874(CHEMBL4176611)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of FITC-Ahx-Bid-OH binding to mouse DN150/DC25 Mcl-1 after 2 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Paris-Saclay University

Curated by ChEMBL
LigandPNGBDBM50314874(CHEMBL4176611)
Affinity DataKi:  2.74E+3nMAssay Description:Inhibition of FITC-AhxBak-OH binding to human 45-84/C37 Bcl-xL after 2 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details Article
PubMed