BDBM50314847 3'-(1,2,3-Triazol-1-yl)-3'-deoxy-beta-D-thymidine::CHEMBL1092729

SMILES Cc1cn([C@H]2C[C@@H]([C@@H](CO)O2)n2ccnn2)c(=O)[nH]c1=O

InChI Key InChIKey=CPWUCLYZTKEZPT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50314847   

TargetThymidine kinase(HHV-1)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314847(3'-(1,2,3-Triazol-1-yl)-3'-deoxy-beta-D-thymidine ...)
Affinity DataIC50: 2.12E+5nMAssay Description:Inhibition of HSV1 thymidine kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetDeoxynucleoside kinase(Fruit fly)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314847(3'-(1,2,3-Triazol-1-yl)-3'-deoxy-beta-D-thymidine ...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of Drosophila melanogaster multifunctional deoxynucleoside kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314847(3'-(1,2,3-Triazol-1-yl)-3'-deoxy-beta-D-thymidine ...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed