BDBM50314842 3'-Deoxy-3'-(5-phenyl-1,2,3-triazol-1-yl)-beta-D-thymidine::CHEMBL1090869

SMILES Cc1cn([C@H]2C[C@@H]([C@@H](CO)O2)n2nncc2-c2ccccc2)c(=O)[nH]c1=O

InChI Key InChIKey=ZGLKLXLPRAAAMO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50314842   

TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314842(3'-Deoxy-3'-(5-phenyl-1,2,3-triazol-1-yl)-beta-D-t...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314842(3'-Deoxy-3'-(5-phenyl-1,2,3-triazol-1-yl)-beta-D-t...)
Affinity DataIC50: 4.45E+5nMAssay Description:Inhibition of HSV1 thymidine kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetDeoxynucleoside kinase(Fruit fly)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314842(3'-Deoxy-3'-(5-phenyl-1,2,3-triazol-1-yl)-beta-D-t...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of Drosophila melanogaster multifunctional deoxynucleoside kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed