BDBM50314790 CHEMBL1092013::N-Cyclopropyl-3-(1-(2-fluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-5-yl)-4-methylbenzamide

SMILES Cc1ccc(cc1-c1cc2cnn(-c3ccccc3F)c2n(C)c1=O)C(=O)NC1CC1

InChI Key InChIKey=GYWNOAVEKDTRBQ-UHFFFAOYSA-N

Data  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50314790   

TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50314790(N-Cyclopropyl-3-(1-(2-fluorophenyl)-7-methyl-6-oxo...)
Affinity DataKd:  0.180nMAssay Description:Binding affinity to p38alpha by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314790(N-Cyclopropyl-3-(1-(2-fluorophenyl)-7-methyl-6-oxo...)
Affinity DataKd:  4.00E+4nMAssay Description:Binding affinity to Kdr by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50314790(N-Cyclopropyl-3-(1-(2-fluorophenyl)-7-methyl-6-oxo...)
Affinity DataKd:  4.00E+4nMAssay Description:Binding affinity to Lck by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314790(N-Cyclopropyl-3-(1-(2-fluorophenyl)-7-methyl-6-oxo...)
Affinity DataKd:  1.70E+3nMAssay Description:Binding affinity to c-Kit by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed