BDBM50314723 CHEMBL1090041::endo-(S)-N-(4-fluorobenzyl)-4-(3-(2-methyl-3H-imidazo[4,5-b]pyridin-3-yl)-8-azabicyclo[3.2.1]octan-8-yl)-2-phenylbutanamide::exo-(S)-N-(4-fluorobenzyl)-4-(3-(2-methyl-3H-imidazo[4,5-b]pyridin-3-yl)-8-azabicyclo[3.2.1]octan-8-yl)-2-phenylbutanamide

SMILES Cc1nc2cccnc2n1C1C[C@H]2CC[C@H](C1)N2CC[C@H](C(=O)NCc1ccc(F)cc1)c1ccccc1

InChI Key InChIKey=HUJMMKROGZIWHI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314723   

TargetC-C chemokine receptor type 5(Human)
Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50314723(exo-(S)-N-(4-fluorobenzyl)-4-(3-(2-methyl-3H-imida...)
Affinity DataIC50: 14.4nMAssay Description:Antagonist activity at CCR5 receptor expressed in CHO cells assessed as inhibition of RANTES-induced [32S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed