BDBM50314722 CHEMBL1093331::endo-(S)-methyl 4-(3-(2-methyl-3H-imidazo[4,5-b]pyridin-3-yl)-8-azabicyclo[3.2.1]octan-8-yl)-2-phenylbutanoate::exo-(S)-methyl 4-(3-(2-methyl-3H-imidazo[4,5-b]pyridin-3-yl)-8-azabicyclo[3.2.1]octan-8-yl)-2-phenylbutanoate

SMILES COC(=O)[C@@H](CCN1[C@@H]2CC[C@@H]1CC(C2)n1c(C)nc2cccnc12)c1ccccc1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314722   

TargetC-C chemokine receptor type 5(Human)
Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50314722(endo-(S)-methyl 4-(3-(2-methyl-3H-imidazo[4,5-b]py...)
Affinity DataIC50: 112nMAssay Description:Antagonist activity at CCR5 receptor expressed in CHO cells assessed as inhibition of RANTES-induced [32S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed