BDBM50314660 2-(4-(3-(2-chloro-3,6-difluorophenoxy)propyl)benzyl)-N-cyclopropyl-N-(2,3-dichlorobenzyl)-3-(methylamino)propanamide::CHEMBL1091040

SMILES CNCC(Cc1ccc(CCCOc2c(F)ccc(F)c2Cl)cc1)C(=O)N(Cc1cccc(Cl)c1Cl)C1CC1

InChI Key InChIKey=AUJWASLBKNLABL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314660   

TargetRenin(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50314660(2-(4-(3-(2-chloro-3,6-difluorophenoxy)propyl)benzy...)
Affinity DataIC50: 1.90nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetRenin(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50314660(2-(4-(3-(2-chloro-3,6-difluorophenoxy)propyl)benzy...)
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant renin in human citreated-plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed