BDBM50314563 3-(1-(3-(4-(pyrimidin-2-yl)piperazin-1-yl)propylamino)pyridazino[4,5-b]indolizin-4-yl)benzonitrile::CHEMBL1089686

SMILES N#Cc1cccc(c1)-c1nnc(NCCCN2CCN(CC2)c2ncccn2)c2cc3ccccn3c12

InChI Key InChIKey=KGVFUTVFZWTLLX-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314563   

LigandPNGBDBM50314563(3-(1-(3-(4-(pyrimidin-2-yl)piperazin-1-yl)propylam...)
Affinity DataKi:  1.03E+3nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314563(3-(1-(3-(4-(pyrimidin-2-yl)piperazin-1-yl)propylam...)
Affinity DataKi:  3.35E+3nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4D4 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed