BDBM50314512 5-(2,3-dimethylphenyl)-N-ethyl-N-(6-methoxypyridin-3-yl)pyrazine-2-carboxamide::CHEMBL1090654

SMILES CCN(C(=O)c1cnc(cn1)-c1cccc(C)c1C)c1ccc(OC)nc1

InChI Key InChIKey=NSJAQLDCCBDFPD-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50314512   

TargetOxytocin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314512(5-(2,3-dimethylphenyl)-N-ethyl-N-(6-methoxypyridin...)
Affinity DataKi:  25nMAssay Description:Antagonist activity at human cloned OT receptor by cell based beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314512(5-(2,3-dimethylphenyl)-N-ethyl-N-(6-methoxypyridin...)
Affinity DataKi:  2.83E+3nMAssay Description:Antagonist activity at human cloned vasopressin V2 receptor by cell based beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314512(5-(2,3-dimethylphenyl)-N-ethyl-N-(6-methoxypyridin...)
Affinity DataKi:  4.72E+5nMAssay Description:Antagonist activity at human cloned vasopressin V1A receptor by cell based beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed