BDBM50314511 CHEMBL1092458::N-ethyl-5-(3-fluoro-2-methylphenyl)-N-(6-methoxypyridin-3-yl)pyrazine-2-carboxamide

SMILES CCN(C(=O)c1cnc(cn1)-c1cccc(F)c1C)c1ccc(OC)nc1

InChI Key InChIKey=SYYCAJHVEXJGJI-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50314511   

TargetOxytocin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314511(N-ethyl-5-(3-fluoro-2-methylphenyl)-N-(6-methoxypy...)
Affinity DataKi:  29nMAssay Description:Antagonist activity at human cloned OT receptor by cell based beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314511(N-ethyl-5-(3-fluoro-2-methylphenyl)-N-(6-methoxypy...)
Affinity DataKi:  5.90E+3nMAssay Description:Antagonist activity at human cloned vasopressin V1A receptor by cell based beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314511(N-ethyl-5-(3-fluoro-2-methylphenyl)-N-(6-methoxypy...)
Affinity DataKi:  3.43E+5nMAssay Description:Antagonist activity at human cloned vasopressin V2 receptor by cell based beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed