BDBM50314504 CHEMBL1089025::N-ethyl-N-(6-methoxypyridin-3-yl)-5-o-tolylpyrazine-2-carboxamide

SMILES CCN(C(=O)c1cnc(cn1)-c1ccccc1C)c1ccc(OC)nc1

InChI Key InChIKey=GZJDGINZCFBGRB-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50314504   

TargetOxytocin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314504(N-ethyl-N-(6-methoxypyridin-3-yl)-5-o-tolylpyrazin...)
Affinity DataKi:  129nMAssay Description:Antagonist activity at human cloned OT receptor by cell based beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314504(N-ethyl-N-(6-methoxypyridin-3-yl)-5-o-tolylpyrazin...)
Affinity DataKi:  2.30E+3nMAssay Description:Antagonist activity at human cloned vasopressin V1A receptor by cell based beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314504(N-ethyl-N-(6-methoxypyridin-3-yl)-5-o-tolylpyrazin...)
Affinity DataKi: >1.00E+4nMAssay Description:Antagonist activity at human cloned vasopressin V2 receptor by cell based beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed