BDBM50314338 (Z)-1-(1-methyl-3-((3-oxo-5-(3-pyridin-3-ylureido)benzofuran-2(3H)-ylidene)methyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-N-(pyridin-3-ylmethyl)piperidine-4-carboxamide::CHEMBL1091703

SMILES Cn1cc(\C=C2/Oc3ccc(NC(=O)Nc4cccnc4)cc3C2=O)c2c(ccnc12)N1CCC(CC1)C(=O)NCc1cccnc1

InChI Key InChIKey=AWYQPFBZFZNCSS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314338   

LigandPNGBDBM50314338((Z)-1-(1-methyl-3-((3-oxo-5-(3-pyridin-3-ylureido)...)
Affinity DataIC50: 4.04E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314338((Z)-1-(1-methyl-3-((3-oxo-5-(3-pyridin-3-ylureido)...)
Affinity DataIC50: 9nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed