BDBM50314292 3-benzyl-1-(4-bromophenyl)-1-(1-cyclopentylpiperidin-4-yl)urea::CHEMBL1094028

SMILES Brc1ccc(cc1)N(C1CCN(CC1)C1CCCC1)C(=O)NCc1ccccc1

InChI Key InChIKey=DLEHGKOYLBSEGL-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50314292   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314292(3-benzyl-1-(4-bromophenyl)-1-(1-cyclopentylpiperid...)
Affinity DataIC50: 178nMAssay Description:Inhibition of human ERG by ion works assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314292(3-benzyl-1-(4-bromophenyl)-1-(1-cyclopentylpiperid...)
Affinity DataIC50: 178nMAssay Description:Displacement of [3H]dofetilide from human recombinant ERG by Competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314292(3-benzyl-1-(4-bromophenyl)-1-(1-cyclopentylpiperid...)
Affinity DataKi:  10nMAssay Description:Antagonist activity at human recombinant histamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314292(3-benzyl-1-(4-bromophenyl)-1-(1-cyclopentylpiperid...)
Affinity DataKi:  10nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed