BDBM50314220 (R)-4-acetamido-2-(4-bromophenylsulfonamido)-N-hydroxybutanamide::CHEMBL1093690

SMILES CC(=O)NCC[C@@H](NS(=O)(=O)c1ccc(Br)cc1)C(=O)NO

InChI Key InChIKey=XXZNXULRAJJTRV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50314220   

TargetMatrix metalloproteinase-14(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50314220((R)-4-acetamido-2-(4-bromophenylsulfonamido)-N-hyd...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant MMP14 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50314220((R)-4-acetamido-2-(4-bromophenylsulfonamido)-N-hyd...)
Affinity DataIC50: 190nMAssay Description:Inhibition of MMP9 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50314220((R)-4-acetamido-2-(4-bromophenylsulfonamido)-N-hyd...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of MMP1 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50314220((R)-4-acetamido-2-(4-bromophenylsulfonamido)-N-hyd...)
Affinity DataIC50: 190nMAssay Description:Inhibition of MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314220((R)-4-acetamido-2-(4-bromophenylsulfonamido)-N-hyd...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant ADAM17 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314220((R)-4-acetamido-2-(4-bromophenylsulfonamido)-N-hyd...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human recombinant ADAM10 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed