BDBM50314163 1-(1-(3-(3-(3-(2-(benzylamino)ethylthio)-4-(trifluoromethyl)phenyl)-5-(methylsulfonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-1-yl)propyl)piperidin-4-yl)pyrrolidin-2-one::CHEMBL1093951

SMILES CS(=O)(=O)N1CCc2c(C1)c(nn2CCCN1CCC(CC1)N1CCCC1=O)-c1ccc(c(SCCNCc2ccccc2)c1)C(F)(F)F

InChI Key InChIKey=PSWIIHWHAUAYDL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314163   

TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314163(1-(1-(3-(3-(3-(2-(benzylamino)ethylthio)-4-(triflu...)
Affinity DataIC50: 700nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50314163(1-(1-(3-(3-(3-(2-(benzylamino)ethylthio)-4-(triflu...)
Affinity DataIC50: 460nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as inhibition of invariant chain degradationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed