BDBM50314146 (S)-4-(2-(4-fluorophenyl)-5-(4-methoxybenzyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-3-yl)-N-propylpyrimidin-2-amine::CHEMBL1094013

SMILES CCCNc1nccc(n1)-c1c(nc2CC[C@@H](Cc3ccc(OC)cc3)n12)-c1ccc(F)cc1

InChI Key InChIKey=XTEXFYJKENTXMP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314146   

TargetMitogen-activated protein kinase 10(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314146((S)-4-(2-(4-fluorophenyl)-5-(4-methoxybenzyl)-6,7-...)
Affinity DataIC50: 10.9nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314146((S)-4-(2-(4-fluorophenyl)-5-(4-methoxybenzyl)-6,7-...)
Affinity DataIC50: 54nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed