BDBM50314125 (S,E)-Ethyl 4-((S)-2-(tert-Butoxycarbonylamino)-2-phenylacetamido)-7-oxo-7-(tritylamino)hept-2-enoate::CHEMBL1090281

SMILES CCOC(=O)\C=C\[C@H](CCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)[C@@H](NC(=O)OC(C)(C)C)c1ccccc1

InChI Key InChIKey=RBIOEWRVNCMSBI-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50314125   

TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50314125((S,E)-Ethyl 4-((S)-2-(tert-Butoxycarbonylamino)-2-...)
Affinity DataKi:  300nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain using low concentration of enzyme by standard fluorescence assay in presence of de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50314125((S,E)-Ethyl 4-((S)-2-(tert-Butoxycarbonylamino)-2-...)
Affinity DataKi:  400nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain using high concentration of enzyme by standard fluorescence assay in presence of d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50314125((S,E)-Ethyl 4-((S)-2-(tert-Butoxycarbonylamino)-2-...)
Affinity DataKi:  470nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50314125((S,E)-Ethyl 4-((S)-2-(tert-Butoxycarbonylamino)-2-...)
Affinity DataKi:  640nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain using low concentration of enzyme by standard fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50314125((S,E)-Ethyl 4-((S)-2-(tert-Butoxycarbonylamino)-2-...)
Affinity DataKi:  640nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain using high concentration of enzyme by standard fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed