BDBM50314108 CHEMBL1092169::N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-(2-hydroxy-2-methylpropanoyl)furo[2,3-b]pyridin-3-yl)-2-hydroxyacetamide

SMILES CC(C)(O)C(=O)c1oc2nc(-c3ccccc3Cl)c(cc2c1NC(=O)CO)-c1ccc(Cl)cc1

InChI Key InChIKey=NLFVFVQFPLEKDA-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50314108   

TargetCytochrome P450 3A4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314108(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-(2-hydr...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314108(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-(2-hydr...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314108(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-(2-hydr...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314108(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-(2-hydr...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314108(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-(2-hydr...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314108(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-(2-hydr...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of human ERG potassium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314108(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-(2-hydr...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314108(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-(2-hydr...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314108(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-(2-hydr...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of cannabinoid CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314108(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-(2-hydr...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed