BDBM50314082 CHEMBL1089950

SMILES CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(C)=O)[C@@H](C)O

InChI Key InChIKey=GRNGOJKQKRCTFF-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50314082   

TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314082(CHEMBL1089950)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314082(CHEMBL1089950)
Affinity DataKd:  2.60E+3nMpH: 6.0Assay Description:Binding affinity to soluble human FcRn at pH 6 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314082(CHEMBL1089950)
Affinity DataKd:  1.80E+4nMpH: 7.4Assay Description:Binding affinity to soluble human FcRn at pH 7.4 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed